Description

2,2-Dimethyl-1,3-Dioxolane-4-Methanol CAS NO 100-79-8 is a versatile chiral building block and solvent, primarily recognized as the protected form of (R)- or (S)-Glyceraldehyde. Its value lies in its ability to introduce stereochemistry and functional groups in complex organic syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and fine chemicals.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material for the production of antiviral drugs, β-blockers, and other active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Synthesis: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals where optical purity is critical.
• Polymer Chemistry: Acts as a monomer or modifying agent for producing specialized polymers with unique properties.
• Academic and R&D Laboratories: A fundamental reagent for methodological development in asymmetric synthesis and carbohydrate chemistry.
• Solvent for Specialized Reactions: Functions as a polar aprotic solvent in certain sensitive chemical transformations.

Basic Information

Product Name	2,2-Dimethyl-1,3-Dioxolane-4-Methanol
CAS No.	100-79-8
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	Isopropylidene Glycerol; (R,S)-1,2-Isopropylidene Glycerol; (±)-1,2-Isopropylidene Glycerol; 2,2-Dimethyl-1,3-dioxolane-4-methanol; Solketal; Glycerol 1,2-Acetonide; 1,2-O-Isopropylidene Glycerol; 1,2-O-Isopropylidene-rac-glycerol
EINECS	202-889-5

Quality Control

We supply 2,2-Dimethyl-1,3-Dioxolane-4-Methanol in various purity grades, from technical to high-purity, to meet diverse application needs. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles are available upon request. We adhere to cGMP and ISO 9001 quality management principles for consistent batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic or specified enantiomeric excess
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.432 - 1.436
Specific Gravity (20°C)	1.064 - 1.072

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.