Description

1-(Piperidin-3-Ylcarbonyl)-1,2,3,4-Tetrahydroquinoline is a sophisticated heterocyclic organic compound featuring a tetrahydroquinoline scaffold fused with a piperidine carbonyl moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly those targeting neurological and central nervous system pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially for central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a core scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Used in the development of novel ligands for various receptors and enzymes due to its privileged piperidine-quinoline structure.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: An intermediate for synthesizing more complex, high-value specialty chemicals used in agrochemical or material science research.

Basic Information

Product Name	1-(Piperidin-3-Ylcarbonyl)-1,2,3,4-Tetrahydroquinoline
CAS No.	856088-18-1
Molecular Formula	C15H20N2O
Molecular Weight	244.33 g/mol
Synonyms	1-(Piperidine-3-carbonyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-1-(3-piperidinylcarbonyl)quinoline; 1-(1,2,3,4-Tetrahydroquinolin-1-yl)-3-piperidin-1-ylpropan-1-one (tautomer); 856088-18-1; Quinoline, 1,2,3,4-tetrahydro-1-(3-piperidinylcarbonyl)-; 3-(1,2,3,4-Tetrahydroquinoline-1-carbonyl)piperidine
EINECS	Contact for details

Quality Control

Our production of 1-(Piperidin-3-Ylcarbonyl)-1,2,3,4-Tetrahydroquinoline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.