Description

6-Methoxy-Pyridine-2-Carboxylic Acid Hydrazide is a versatile heterocyclic building block and key synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in the reactive hydrazide functional group, which enables the construction of complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides, leveraging its pyridine-hydrazide scaffold.
• Ligand and Chelating Agent Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal complexation studies.
• Heterocyclic Chemistry Research: A fundamental building block for constructing complex fused-ring systems like pyrazoles, triazoles, and other N-heterocycles in academic and industrial R&D.
• Chemical Biology Probe Development: Employed in the creation of molecular probes and biochemical tools for studying enzyme inhibition and cellular pathways.

Basic Information

Product Name	6-Methoxy-Pyridine-2-Carboxylic Acid Hydrazide
CAS No.	855784-42-8
Molecular Formula	C7H9N3O2
Molecular Weight	167.16 g/mol
Synonyms	6-Methoxypicolinohydrazide; 2-Pyridinecarboxylic acid, 6-methoxy-, hydrazide; 6-Methoxy-2-pyridinecarboxylic acid hydrazide; 6-Methoxypicolinic acid hydrazide; Picolinic acid, 6-methoxy-, hydrazide; 6-Methoxypicolinoyl hydrazide; 6-Methoxy-2-hydrazinocarbonylpyridine; 855784-42-8
EINECS	Contact for details

Quality Control

Our 6-Methoxy-Pyridine-2-Carboxylic Acid Hydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.