Description

Kynurenic Acid, 3,5-Dichloro- (5Ci) is a halogenated derivative of the endogenous neuroactive compound kynurenic acid. This modified analog is of significant interest in advanced pharmaceutical research and development, particularly for probing specific biological pathways and receptor interactions. It serves as a critical building block and reference standard for medicinal chemists and neuroscientists in the global life sciences sector.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel central nervous system (CNS) targeting drugs.
• Biochemical Research: Used as a specialized tool compound to study the kynurenine pathway and its role in neurological disorders.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new modulators of glutamate and nicotinic receptors.
• Academic Research: Utilized in university and institutional labs for fundamental research in neuropharmacology and neurochemistry.

Basic Information

Product Name	Kynurenic Acid, 3,5-Dichloro- (5Ci)
CAS No.	855634-12-7
Molecular Formula	C10H5Cl2NO3
Molecular Weight	258.06 g/mol
Synonyms	3,5-Dichlorokynurenic Acid; 3,5-Dichloro-4-hydroxyquinoline-2-carboxylic Acid; 3,5-Dichloro-4-hydroxy-2-quinolinecarboxylic Acid; 2-Quinolinecarboxylic acid, 3,5-dichloro-4-hydroxy-; 5Ci-Kynurenic Acid derivative
EINECS	Contact for details

Quality Control

Our Kynurenic Acid, 3,5-Dichloro- (5Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.