Description

Kynurenic Acid, 3,7-Dichloro- (5Ci) is a halogenated derivative of the endogenous tryptophan metabolite kynurenic acid. This compound is a valuable synthetic intermediate and research chemical, primarily utilized in the development and study of novel pharmaceutical agents and biochemical tools. It is particularly relevant for researchers and development teams in the pharmaceutical, biotechnology, and life science sectors focusing on neurochemistry, metabolic pathways, and medicinal chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate or precursor in the synthesis of novel drug candidates targeting neurological and metabolic disorders.
• Biochemical Research: Used as a reference standard or tool compound in studies investigating the kynurenine pathway, NMDA receptor modulation, and related biological mechanisms.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop analogs with optimized potency, selectivity, and pharmacokinetic properties.
• Academic Research: Utilized in university and institutional labs for fundamental research in neuropharmacology, biochemistry, and chemical biology.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects and scale-up activities.

Basic Information

Product Name	Kynurenic Acid, 3,7-Dichloro- (5Ci)
CAS No.	855634-10-5
Molecular Formula	C10H5Cl2NO3
Molecular Weight	258.06 g/mol
Synonyms	3,7-Dichlorokynurenic Acid; 3,7-Dichloro-4-hydroxyquinoline-2-carboxylic Acid; 3,7-Dichloro-4-hydroxy-2-quinolinecarboxylic Acid; 4-Hydroxy-3,7-dichloroquinoline-2-carboxylic Acid; 5Ci-Kynurenic Acid derivative; Kynurenic acid dichloro derivative
EINECS	Contact for details

Quality Control

Our Kynurenic Acid, 3,7-Dichloro- (5Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.