Description

Kynurenic Acid, 3,7-Dichloro-, Et Ester (5Ci) is a high-purity, halogenated derivative of kynurenic acid, specifically designed for advanced research and development. This compound is valued for its role as a specialized biochemical tool in the study of neuropharmacology and metabolic pathways. It is primarily sought by pharmaceutical researchers, contract research organizations (CROs), and academic institutions engaged in neuroscience, medicinal chemistry, and biomarker discovery programs.

Application

• Neuroscience Research: Acts as a reference standard or analytical standard in studies investigating the kynurenine pathway and its role in neurological disorders.
• Medicinal Chemistry: Serves as a key synthetic intermediate or pharmacophore for developing novel therapeutic agents targeting specific receptors or enzymes.
• Biochemical Assay Development: Used in the development and validation of high-throughput screening (HTS) assays and analytical methods (HPLC, LC-MS).
• Metabolite Analysis: Employed as a calibration standard in quantitative bioanalysis to study drug metabolism and endogenous metabolite profiles.
• Academic & Institutional Research: Supports fundamental research in universities and government labs focused on neuroinflammation, neurodegeneration, and tryptophan metabolism.

Basic Information

Product Name	Kynurenic Acid, 3,7-Dichloro-, Et Ester (5Ci)
CAS No.	855634-09-2
Molecular Formula	C14H11Cl2NO4
Molecular Weight	328.15 g/mol
Synonyms	3,7-Dichlorokynurenic Acid Ethyl Ester; Ethyl 3,7-Dichloro-4-hydroxyquinoline-2-carboxylate; 5Ci-Kynurenic Acid Derivative; 3,7-Dichloro-KYNA-OEt; Kynurenic acid ethyl ester, 3,7-dichloro-; Quinoline-2-carboxylic acid, 4-hydroxy-3,7-dichloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Kynurenic Acid, 3,7-Dichloro-, Et Ester (5Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality management standards to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.