Description

3-Bromo-8-Fluoroquinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is specifically engineered to serve as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel quinolone-based antibiotics, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of next-generation fungicides and herbicides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Catalyst Ligand Synthesis: Utilized to create sophisticated nitrogen-containing ligands for transition metal catalysis.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	3-Bromo-8-Fluoroquinoline
CAS No.	855477-01-9
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	8-Fluoro-3-bromoquinoline; Quinoline, 3-bromo-8-fluoro-; 3-Bromo-8-fluoro-quinoline; 855477-01-9; FCAS 855477-01-9
EINECS	Contact for details

Quality Control

Our 3-Bromo-8-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.