Description

4-Hydroxybenzo[H]Quinoline-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused quinoline structure with both phenolic and carboxylic acid functionalities makes it a versatile intermediate for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a chelating agent or a backbone for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Acts as a building block for electron-transport materials, light-emitting compounds, and other components in OLEDs and organic photovoltaics.
• Fluorescent Probe and Dye Chemistry: Utilized in the design of fluorescent markers, sensors, and specialty dyes due to its inherent photophysical properties.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in discovery research.

Basic Information

Product Name	4-Hydroxybenzo[H]Quinoline-2-Carboxylic Acid
CAS No.	855283-82-8
Molecular Formula	C₁₄H₉NO₃
Molecular Weight	239.23 g/mol
Synonyms	4-Hydroxybenzo[h]quinoline-2-carboxylic acid; 2-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-; 4-Oxo-1,4-dihydrobenzo[h]quinoline-2-carboxylic acid; Benzo[h]quinoline-2-carboxylic acid, 4-hydroxy-; 4-Hydroxy-1-azanaphthalene-2-carboxylic acid; AQCA (common abbreviation); 1,4-Dihydro-4-oxobenzo[h]quinoline-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxybenzo[H]Quinoline-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (HPLC, NMR, IR) is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Due to its acidic nature, store away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.