Description

4-Quinolinecarbonyl Chloride,7-Methyl-2-Phenyl-,Hydrochloride(1:1) is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its role as a key building block for constructing complex heterocyclic frameworks, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop new compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the 4-quinolinecarbonyl moiety into more complex molecules in academic and industrial R&D.
• Material Science: Potential intermediate for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for client projects.

Basic Information

Product Name	4-Quinolinecarbonyl Chloride,7-Methyl-2-Phenyl-,Hydrochloride(1:1)
CAS No.	854863-93-7
Molecular Formula	C18H14ClNO•HCl
Molecular Weight	332.22 g/mol (for the hydrochloride salt)
Synonyms	7-Methyl-2-phenylquinoline-4-carbonyl chloride hydrochloride; 2-Phenyl-7-methylquinoline-4-carbonyl chloride hydrochloride; 4-Carbamoyl-7-methyl-2-phenylquinoline hydrochloride (related); Quinoline-4-carbonyl chloride, 7-methyl-2-phenyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarbonyl Chloride,7-Methyl-2-Phenyl-,Hydrochloride(1:1) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.