Description

4-Aminocyclohexanecarboxylic Acid Hydrochloride is a high-purity organic salt derivative of a functionalized cyclohexane, serving as a critical chiral building block and intermediate in advanced chemical synthesis. Its value lies in providing a rigid, substituted cyclohexane scaffold with both amino and carboxylic acid functionalities, protected as the hydrochloride salt for enhanced stability and handling. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing novel active pharmaceutical ingredients (APIs), peptidomimetics, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Peptidomimetics & Conformationally Restricted Peptides: Used to introduce rigid, cyclohexane-based backbones into peptide analogs to enhance metabolic stability and receptor selectivity.
• Ligand Synthesis for Catalysis: Serves as a precursor for constructing chiral ligands used in asymmetric synthesis and homogeneous catalysis.
• Advanced Material Monomers: Can be utilized in the synthesis of specialized polyamides or other polymers requiring cycloaliphatic structures with functional handles.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes or affinity tags to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting complex, high-value molecules.

Basic Information

Product Name	4-Aminocyclohexanecarboxylic Acid Hydrochloride
CAS No.	854446-76-7
Molecular Formula	C7H14ClNO2
Molecular Weight	179.64 g/mol
Synonyms	trans-4-Aminocyclohexanecarboxylic acid hydrochloride; 4-Amino-1-cyclohexanecarboxylic acid HCl; 4-Aminocyclohexane-1-carboxylic acid hydrochloride; (1r,4r)-4-aminocyclohexane-1-carboxylic acid hydrochloride; (1s,4s)-4-aminocyclohexane-1-carboxylic acid hydrochloride; 4-ACCA HCl; 4-Amino-CHCA HCl
EINECS	Contact for details

Quality Control

Our 4-Aminocyclohexanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.