Description

6-Bromo-4-Chloro-7-Fluoro-3-Nitroquinoline is a high-purity, multi-substituted quinoline derivative serving as a critical building block in advanced organic synthesis. Its complex halogenated and nitrated structure makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and antiviral research.
• Agrochemical Development: Used in creating advanced fungicides and pesticides, leveraging the bioactivity of the halogenated quinoline core.
• Material Science Research: Serves as a building block for organic semiconductors, ligands for catalysis, and photoactive compounds due to its electron-deficient aromatic system.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, where the bromo and chloro groups offer orthogonal reactivity.
• Academic & R&D: Utilized in universities and corporate R&D labs for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-4-Chloro-7-Fluoro-3-Nitroquinoline
CAS No.	853908-81-3
Molecular Formula	C9H3BrClFN2O2
Molecular Weight	305.49 g/mol
Synonyms	6-Bromo-4-chloro-7-fluoro-3-nitroquinoline; 4-Chloro-6-bromo-7-fluoro-3-nitroquinoline; 3-Nitro-6-bromo-4-chloro-7-fluoroquinoline; Quinoline, 6-bromo-4-chloro-7-fluoro-3-nitro-; 853908-81-3; BCFNQ; 6-Br-4-Cl-7-F-3-NO2-Quinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-7-Fluoro-3-Nitroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere if prolonged exposure is expected during use.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.