Description

4-(Piperidin-4-Yloxy)Quinazoline is a high-purity, advanced pharmaceutical intermediate and research chemical with the CAS number 853687-25-9. This compound is valued for its role as a key building block in the synthesis of novel bioactive molecules, particularly in kinase inhibitor research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a scaffold or reference standard in structure-activity relationship (SAR) studies and high-throughput screening assays.
• Academic Research: Employed in universities and research institutes for medicinal chemistry projects and the development of new chemical entities.
• Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and process development under cGMP conditions.
• Library Synthesis: Serves as a core structure for generating diverse compound libraries for drug discovery programs.

Basic Information

Product Name	4-(Piperidin-4-Yloxy)Quinazoline
CAS No.	853687-25-9
Molecular Formula	C13H15N3O
Molecular Weight	229.28 g/mol
Synonyms	4-(4-Piperidyloxy)quinazoline; Quinazoline, 4-(4-piperidinyloxy)-; 4-Quinazolinol, 4-(4-piperidinyloxy)-; 853687-25-9; 4-(Piperidin-4-yloxy)quinazoline; 4-(4-Piperidinoloxy)quinazoline
EINECS	Contact for details

Quality Control

Our 4-(Piperidin-4-Yloxy)Quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.