Description

8-Methoxy-2,3-Dihydrobenzo[B][1,4]Dioxine-6-Carboxylic Acid CAS NO 852956-36-6 is a high-purity, functionalized benzodioxine derivative serving as a critical advanced pharmaceutical intermediate and organic synthesis building block. Its unique molecular scaffold, featuring both a methoxy-substituted benzodioxine ring and a carboxylic acid group, makes it invaluable for constructing complex molecules with specific biological activities. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides due to its benzodioxine core structure.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands in catalytic systems and material science.
• Organic Electronic Materials: Potential monomer for constructing conjugated polymers used in organic light-emitting diodes (OLEDs) or semiconductors.
• Flavor and Fragrance Industry: Intermediate for synthesizing complex aroma chemicals with benzodioxane characteristics.
• Academic and Contract Research: Used in university and CRO laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	8-Methoxy-2,3-Dihydrobenzo[B][1,4]Dioxine-6-Carboxylic Acid
CAS No.	852956-36-6
Molecular Formula	C10H10O5
Molecular Weight	210.18 g/mol
Synonyms	6-Carboxy-8-methoxy-2,3-dihydro-1,4-benzodioxine; 8-Methoxy-2,3-dihydro-1,4-benzodioxine-6-carboxylic acid; 8-Methoxy-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxylic acid; 1,4-Benzodioxine-6-carboxylic acid, 8-methoxy-2,3-dihydro-; 852956-36-6; 8-Methoxy-2,3-dihydro-1,4-benzodioxin-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 8-Methoxy-2,3-Dihydrobenzo[B][1,4]Dioxine-6-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting specifications for use in sensitive applications like pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.