Description

(8A,9S)-10,11-Dihydro-6'-Methoxy-Cinchonan-9-Amine is a high-purity, stereochemically defined cinchona alkaloid derivative. This compound serves as a critical chiral intermediate and ligand in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking advanced chiral building blocks and catalysts.

Application

• Asymmetric Synthesis: Employed as a chiral ligand or organocatalyst in stereoselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediates: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Catalyst Development: Used in the research and preparation of novel catalytic systems for industrial-scale enantioselective processes.
• Analytical Chiral Resolution: Can be utilized in the development of chiral stationary phases for HPLC to separate enantiomers.
• Fine Chemical Production: Integral to the manufacture of complex, high-value specialty chemicals where stereochemistry dictates function.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and process optimization.

Basic Information

Product Name	(8A,9S)-10,11-Dihydro-6'-Methoxy-Cinchonan-9-Amine
CAS No.	852913-53-2
Molecular Formula	C20H26N2O
Molecular Weight	310.44 g/mol
Synonyms	(8α,9S)-10,11-Dihydro-6'-methoxycinchonan-9-amine; Dihydro-6'-Methoxycinchonan-9-amine; (9S)-10,11-Dihydro-6'-methoxycinchonan-9-amine; Cinchonan-9-amine, 10,11-dihydro-6'-methoxy-, (8α,9S)-; A potential chiral dihydrocinchona alkaloid derivative. Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our (8A,9S)-10,11-Dihydro-6'-Methoxy-Cinchonan-9-Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic and catalytic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.