Description

4-Benzyl-1,5-Dioxo-2,3,4,5-Tetrahydropyrrolo[1,2-A]Quinazoline-3A(1H)-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring quinazoline structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules targeting specific therapeutic pathways. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially in oncology and CNS-related fields.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new pharmacophores with potential biological activity.
• API Development: Employed in the research phase for the development of new Active Pharmaceutical Ingredients (APIs), particularly those with quinazoline-based structures.
• Chemical Biology Probes: Acts as a precursor for creating specialized probes to study enzyme interactions and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	4-Benzyl-1,5-Dioxo-2,3,4,5-Tetrahydropyrrolo[1,2-A]Quinazoline-3A(1H)-Carboxylic Acid
CAS No.	852706-19-5
Molecular Formula	C20H16N2O4
Molecular Weight	348.35 g/mol
Synonyms	4-Benzyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid; 3aH-Pyrrolo[1,2-a]quinazoline-3a-carboxylic acid, 4-(phenylmethyl)-1,5-dioxo-1,2,3,5-tetrahydro-; 852706-19-5; 4-Benzyl-1,5-dioxo-1,2,3,5-tetrahydropyrrolo[1,2-a]quinazoline-3a-carboxylic acid; Pyrroloquinazoline derivative CAS 852706-19-5
EINECS	Contact for details

Quality Control

Our production of 4-Benzyl-1,5-Dioxo-2,3,4,5-Tetrahydropyrrolo[1,2-A]Quinazoline-3A(1H)-Carboxylic Acid adheres to stringent quality protocols suitable for pharmaceutical R&D applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.