Description

3-Bromo-1-Methyl-4-Phenyl-1H-2-Quinolinone is a specialized brominated quinolinone derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromine and quinolinone functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways where the quinolinone scaffold is relevant.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for creating advanced organic materials, such as organic light-emitting diodes (OLEDs) or conductive polymers, where its aromatic and brominated properties are beneficial.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) where the bromine atom serves as an excellent leaving group for further functionalization.
• Academic & Institutional R&D: Utilized in universities and research institutes for methodological studies and the exploration of new chemical reactions involving halogenated heterocycles.
• Ligand and Catalyst Development: Potential use in the design of novel ligands for metal catalysis due to its nitrogen-containing heterocyclic structure.

Basic Information

Product Name	3-Bromo-1-Methyl-4-Phenyl-1H-2-Quinolinone
CAS No.	852203-12-4
Molecular Formula	C₁₆H₁₂BrNO
Molecular Weight	314.18 g/mol
Synonyms	3-Bromo-1-methyl-4-phenylquinolin-2(1H)-one; 1-Methyl-3-bromo-4-phenyl-1H-quinolin-2-one; 3-Bromo-1-methyl-4-phenyl-2(1H)-quinolinone; 852203-12-4; 3-Bromo-1-methyl-4-phenyl-2-quinolone; 1H-2-Quinolinone, 3-bromo-1-methyl-4-phenyl-
EINECS	Contact for details

Quality Control

Our 3-Bromo-1-Methyl-4-Phenyl-1H-2-Quinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your synthetic workflows. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.