Description

Ethyl 3-(Difluoromethyl)-1-Methyl-1H-Pyrazole-5-Carboxylate is a high-purity, fluorinated pyrazole derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, difluoromethyl-substituted scaffold essential for constructing complex molecules with tailored properties. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting metabolic and central nervous system diseases.
• Agrochemical Synthesis: Serves as a precursor for developing next-generation fungicides, herbicides, and insecticides, leveraging the difluoromethyl group for enhanced bioactivity and stability.
• Material Science Research: Used in the development of specialty polymers and advanced materials where the incorporation of fluorine atoms can modify surface properties and stability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 3-(Difluoromethyl)-1-Methyl-1H-Pyrazole-5-Carboxylate
CAS No.	852023-44-0
Molecular Formula	C8H10F2N2O2
Molecular Weight	204.18 g/mol
Synonyms	Ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-5-carboxylate; 5-Carbethoxy-3-(difluoromethyl)-1-methylpyrazole; 1-Methyl-3-(difluoromethyl)-1H-pyrazole-5-carboxylic acid ethyl ester; Ethyl 1-methyl-3-(difluoromethyl)-1H-pyrazole-5-carboxylate; 852023-44-0; DFMPE; 3-(Difluoromethyl)-1-methyl-1H-pyrazole-5-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Difluoromethyl)-1-Methyl-1H-Pyrazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.