Description

4-Chloro-6-Fluoroquinoline-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to the quinoline class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of antimicrobial and anticancer agents. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel quinolone-based antibiotics and chemotherapeutic agents.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the construction of complex molecular libraries.
• Biochemical Research: Serves as a precursor or reference standard in biochemical assays and pharmacological studies targeting specific enzymes or pathways.
• Agrochemical Development: Potential application as an intermediate in the synthesis of new agrochemicals with herbicidal or fungicidal activity.
• Material Science Research: Investigated for use in the development of organic electronic materials or fluorescent probes due to the quinoline core structure.

Basic Information

Product Name	4-Chloro-6-Fluoroquinoline-3-Carboxamide
CAS No.	851973-26-7
Molecular Formula	C₁₀H₆ClFN₂O
Molecular Weight	224.62 g/mol
Synonyms	4-Chloro-6-fluoroquinoline-3-carboxamide; 3-Quinolinecarboxamide, 4-chloro-6-fluoro-; 4-Chloro-6-fluoro-3-quinolinecarboxamide; 851973-26-7; 4-Chloro-6-fluoro-quinoline-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoroquinoline-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.