Description

Ethyl 8-Fluoro-4-Hydroxy-6-Methoxyquinoline-3-Carboxylate is a high-purity, fluorinated quinoline derivative serving as a critical advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluoroquinolone antibiotics and other therapeutic agents targeting bacterial infections.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the quinoline core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of libraries of compounds for high-throughput screening.
• Material Science: Investigated for potential use in the development of organic semiconductors and fluorescent materials due to its conjugated structure.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and contract research organizations (CROs) focused on drug discovery.

Basic Information

Product Name	Ethyl 8-Fluoro-4-Hydroxy-6-Methoxyquinoline-3-Carboxylate
CAS No.	851973-23-4
Molecular Formula	C₁₃H₁₂FNO₄
Molecular Weight	265.24 g/mol
Synonyms	8-Fluoro-4-hydroxy-6-methoxyquinoline-3-carboxylic acid ethyl ester; Ethyl 8-fluoro-4-hydroxy-6-methoxy-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 8-fluoro-4-hydroxy-6-methoxy-, ethyl ester; 851973-23-4; 8-Fluoro-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 8-Fluoro-4-Hydroxy-6-Methoxyquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.