Description

Benzoic Acid, 2-[[3,5-Dichloro-4-[[14-(2-Pyridinyldithio)-3,6,9,12-Tetraoxatetradec-1-Yl]Oxy]Phenyl]Amino]- is a specialized bifunctional chemical compound that integrates a benzoic acid core with a heterocyclic linker and a polyethylene glycol (PEG) spacer. This product matters as a versatile building block and linker molecule, designed for advanced applications in bioconjugation and pharmaceutical research. It is primarily needed by R&D teams and manufacturers in the pharmaceutical, biotech, and diagnostic reagent sectors for developing targeted drug delivery systems and novel chemical probes.

Application

• Bioconjugation Reagent: Used for linking therapeutic molecules (e.g., antibodies, peptides) to drugs, toxins, or imaging agents via cleavable disulfide bonds.
• Prodrug Synthesis: Serves as a key intermediate in the design of prodrugs with targeted release mechanisms.
• Chemical Biology Probes: Enables the creation of activity-based probes for studying enzyme function and protein interactions.
• Polymer Modification: Acts as a functional monomer or cross-linker for synthesizing smart polymers and hydrogels with responsive properties.
• Diagnostic Assay Development: Utilized in the fabrication of diagnostic kits and biosensors that require specific molecular attachment.
• ADC (Antibody-Drug Conjugate) Research: A critical component in the linker-payload complex for next-generation ADCs, facilitating controlled drug release.
• Material Science: Applied in surface functionalization to create bioactive coatings on medical devices or nanoparticles.

Basic Information

Item	Details
Product Name	Benzoic Acid, 2-[[3,5-Dichloro-4-[[14-(2-Pyridinyldithio)-3,6,9,12-Tetraoxatetradec-1-Yl]Oxy]Phenyl]Amino]-
CAS No.	851962-14-6
Molecular Formula	C30H35Cl2N3O7S2
Molecular Weight	684.65 g/mol
Synonyms	2-[[3,5-Dichloro-4-[[14-(2-pyridinyldithio)-3,6,9,12-tetraoxatetradec-1-yl]oxy]phenyl]amino]benzoic acid; PEG4-SPDP Benzoic Acid Derivative; Heterobifunctional PEG Linker with Disulfide and Carboxylate; SS-PEG4-NHS Ester Precursor; 2-Amino-N-(3,5-dichloro-4-((14-(pyridin-2-yldisulfanyl)-3,6,9,12-tetraoxatetradecyl)oxy)phenyl)benzamide acid form; Cleavable ADC Linker Intermediate; Pyridyl disulfide PEG acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid derivative is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, NMR) are provided to confirm identity, purity, and the absence of critical impurities. We adhere to cGMP guidelines for the production of materials intended for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent exposure to atmospheric moisture. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.