Description

(R)-7-Hydroxy-1,4-Dioxaspiro[4.5]decan-8-one is a high-value chiral building block and key synthetic intermediate in advanced organic chemistry. This compound is critical for the enantioselective synthesis of complex molecules, offering precise stereochemical control for researchers and process chemists. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex molecular architectures with defined stereocenters.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	(R)-7-Hydroxy-1,4-Dioxaspiro[4.5]decan-8-one
CAS No.	851764-31-3
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(R)-7-Hydroxy-1,4-dioxaspiro[4.5]decan-8-one; (8R)-8-Hydroxy-1,4-dioxaspiro[4.5]decan-7-one; (R)-8-Hydroxy-7-oxo-1,4-dioxaspiro[4.5]decane; (R)-HDSD; Spiroketal alcohol ketone intermediate
EINECS	Contact for details

Quality Control

Our (R)-7-Hydroxy-1,4-Dioxaspiro[4.5]decan-8-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with stringent purity standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.