Description

2-Chloro-n-{Spiro[1,3-Benzodioxole-2,1''-Cyclohexane]-6-Yl}Acetamide is a high-purity, specialized organic compound featuring a unique spirocyclic structure that combines a benzodioxole moiety with a cyclohexane ring. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and development of new crop protection agents, leveraging its heterocyclic structure.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying biological systems and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2-Chloro-n-{Spiro[1,3-Benzodioxole-2,1''-Cyclohexane]-6-Yl}Acetamide
CAS No.	851722-03-7
Molecular Formula	C15H18ClNO3
Molecular Weight	295.76 g/mol
Synonyms	2-Chloro-N-(spiro[1,3-benzodioxole-2,1'-cyclohexan]-6-yl)acetamide; 2-Chloro-N-(6-spiro[1,3]benzodioxole-2,1'-cyclohexyl)acetamide; 2-Chloroacetamide, N-[spiro(1,3-benzodioxole-2,1'-cyclohexane)-6-yl]-; Acetamide, 2-chloro-N-[spiro[1,3-benzodioxole-2,1'-cyclohexan]-6-yl]-; CAS 851722-03-7; Spiro[1,3-benzodioxole-2,1'-cyclohexane]-6-amine, N-(2-chloroacetyl)- derivative.
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-n-{Spiro[1,3-Benzodioxole-2,1''-Cyclohexane]-6-Yl}Acetamide adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. All materials are characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant documentation for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.