Description

(R)-2-((4-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is a high-value chiral epoxide building block characterized by its trifluoromethylphenoxy functional group. This compound matters for its role as a critical intermediate in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced agrochemicals, where the (R)-configuration and fluorine atoms impart specific biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, including CNS drugs and anti-inflammatory compounds.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides, fungicides, and insecticides with enhanced efficacy.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials and organic semiconductors.
• Asymmetric Catalysis Research: Valuable substrate for studying and developing new catalytic ring-opening reactions and kinetic resolutions.
• Fluorine Chemistry Studies: Essential compound for investigating structure-activity relationships (SAR) influenced by the trifluoromethyl group.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of client-specific fine chemicals and advanced intermediates.

Basic Information

Product Name	(R)-2-((4-(Trifluoromethyl)Phenoxy)Methyl)Oxirane
CAS No.	851528-84-2
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	(R)-4-(Trifluoromethyl)phenyl glycidyl ether; (R)-1-((4-(Trifluoromethyl)phenoxy)methyl)oxirane; (R)-Glycidyl 4-(trifluoromethyl)phenyl ether; (R)-2-[(4-Trifluoromethylphenoxy)methyl]oxirane; (R)-TFMPGE; (R)-Epoxide of 4-(trifluoromethyl)benzyl alcohol; (R)-α-Epoxy-ω-(4-trifluoromethylphenoxy)propane
EINECS	Contact for details

Quality Control

Our (R)-2-((4-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.