Description

2-(Chloromethyl)-6-(4-Chlorophenyl)-3H,4H-Thieno[3,2-D]Pyrimidin-4-One is a high-value heterocyclic organic compound featuring a fused thienopyrimidinone core, serving as a critical synthetic intermediate in advanced chemical research and development. Its unique molecular architecture, incorporating reactive chloromethyl and chlorophenyl substituents, makes it a versatile building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides due to its bioactive heterocyclic structure.
• Material Science: Serves as a building block for creating advanced organic electronic materials and specialty polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Academic & Contract Research: Utilized in university and CRO settings for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	2-(Chloromethyl)-6-(4-Chlorophenyl)-3H,4H-Thieno[3,2-D]Pyrimidin-4-One
CAS No.	851398-76-0
Molecular Formula	C13H8Cl2N2OS
Molecular Weight	311.18 g/mol
Synonyms	2-(Chloromethyl)-6-(4-chlorophenyl)-3,4-dihydrothieno[3,2-d]pyrimidin-4-one; 6-(4-Chlorophenyl)-2-(chloromethyl)-3,4-dihydrothieno[3,2-d]pyrimidin-4-one; Thieno[3,2-d]pyrimidin-4(3H)-one, 2-(chloromethyl)-6-(4-chlorophenyl)-3,4-dihydro-; 851398-76-0; 2-(Chloromethyl)-6-(p-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6-(4-Chlorophenyl)-3H,4H-Thieno[3,2-D]Pyrimidin-4-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.