Description

4-Iodo-n-sec-Butyl-Amphetamine-Hydrochloride is a specialized halogenated amphetamine derivative used as a critical intermediate in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates an iodine atom and a secondary butyl group, making it a versatile building block for creating novel chemical entities. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, neuroscience research, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a key synthetic intermediate in the discovery and development of new therapeutic agents, particularly in central nervous system (CNS) targeting compounds.
• Medicinal Chemistry: Used as a building block for structure-activity relationship (SAR) studies and the synthesis of novel amphetamine analogs for pharmacological evaluation.
• Neuroscience Research: Employed in the synthesis of radioligands or tracer molecules for studying neurotransmitter systems, receptor binding, and metabolic pathways.
• Chemical Synthesis: Acts as a precursor for further functionalization, leveraging the reactive iodine moiety for cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse chemical libraries.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in forensic and pharmaceutical analysis.

Basic Information

Product Name	4-Iodo-n-sec-Butyl-Amphetamine-Hydrochloride
CAS No.	851292-42-7
Molecular Formula	C13H19IN•HCl
Molecular Weight	367.66 g/mol
Synonyms	4-Iodo-N-(sec-butyl)amphetamine hydrochloride; 1-(4-Iodophenyl)-2-(sec-butylamino)propane hydrochloride; 4-Iodo-sec-butylamphetamine HCl; 4-Iodo-N-sec-butyl-1-phenylpropan-2-amine hydrochloride; 1-(4-Iodophenyl)-N-sec-butan-2-ylpropan-2-amine hydrochloride; 4-Iodo-N-(1-methylpropyl)amphetamine hydrochloride; p-Iodo-n-sec-butylamphetamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Iodo-n-sec-Butyl-Amphetamine-Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.