Description

5H-1-Benzazepin-5-One, 1,2,3,4-Tetrahydro-7-(Trifluoromethyl)- is a high-value heterocyclic organic compound featuring a benzazepinone core with a strategically positioned trifluoromethyl group. This molecular architecture is critical for its role as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Acts as a specialty monomer or precursor for advanced polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization studies for the commercial-scale production of complex molecules.

Basic Information

Product Name	5H-1-Benzazepin-5-One, 1,2,3,4-Tetrahydro-7-(Trifluoromethyl)-
CAS No.	851045-54-0
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	7-(Trifluoromethyl)-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; 1,2,3,4-Tetrahydro-7-(trifluoromethyl)-5H-1-benzazepin-5-one; 5H-1-Benzazepin-5-one, 1,2,3,4-tetrahydro-7-(trifluoromethyl)-; 851045-54-0; 7-Trifluoromethyl-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one; Tetrahydrobenzazepinone trifluoromethyl derivative; TFMBZP
EINECS	Contact for details

Quality Control

Our production of 5H-1-Benzazepin-5-One, 1,2,3,4-Tetrahydro-7-(Trifluoromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up work. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.