Description

4-(Aminooxy)Butanoic Acid, Hydrobromide is a specialized organic salt derivative of 4-(aminooxy)butanoic acid, valued for its bifunctional aminooxy and carboxylic acid groups. This compound serves as a critical building block and linker in advanced organic synthesis, particularly for the site-specific conjugation of biomolecules. It is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and life science reagent sectors who require high-purity intermediates for developing targeted therapeutics and diagnostic probes.

Application

• Bioconjugation Reagent: Used for the site-specific modification of proteins, antibodies, and peptides via oxime ligation.
• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates and antibody-drug conjugates (ADCs).
• Crosslinking Agent: Employed in material science and polymer chemistry to create functionalized hydrogels and biomaterials.
• Chemical Biology Probe Synthesis: Facilitates the labeling of biomolecules with fluorophores, affinity tags, or other reporter groups for research.
• Carbohydrate Chemistry: Acts as a linker for the chemoselective attachment of sugars to carriers or surfaces.
• Peptide Synthesis: Used to introduce aminooxy functionality into peptide chains for subsequent ligation strategies.

Basic Information

Product Name	4-(Aminooxy)Butanoic Acid, Hydrobromide
CAS No.	850411-24-4
Molecular Formula	C₄H₁₀BrNO₃
Molecular Weight	200.03 g/mol
Synonyms	4-(Aminooxy)butyric Acid Hydrobromide; 4-Aminoxybutanoic Acid HBr; O-(3-Carboxypropyl)hydroxylamine Hydrobromide; 4-(Hydroxyamino)butyric Acid Hydrobromide; γ-(Aminooxy)butyric Acid Hydrobromide; Butanoic acid, 4-(aminooxy)-, hydrobromide (1:1); Aminooxy-PEG3-acid HBr
EINECS	Contact for details

Quality Control

Our 4-(Aminooxy)Butanoic Acid, Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	98.0 - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.