Description

(1S,4S)-2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene is a highly specific, chiral bicyclic diene compound of significant interest in advanced organic synthesis and materials science research. Its rigid, three-dimensional structure and defined stereochemistry make it a valuable building block for creating complex molecular architectures, particularly in the development of novel ligands, catalysts, and functional organic materials. This compound is primarily utilized by R&D chemists and process development scientists in pharmaceutical, agrochemical, and specialty chemical industries seeking to explore new synthetic pathways and material properties.

Application

• Chiral Ligand Synthesis: Serves as a key precursor for the development of novel, sterically defined ligands used in asymmetric catalysis.
• Pharmaceutical Intermediate: Employed in the research and development of active pharmaceutical ingredients (APIs) requiring complex, stereochemically pure core structures.
• Advanced Material Research: Used as a monomer or building block in the synthesis of polymers and organic frameworks with specific optical or electronic properties.
• Methodology Development: A valuable substrate for testing new synthetic methodologies, particularly those involving stereoselective Diels-Alder or other cycloaddition reactions.
• Agrochemical Research: Investigated for the creation of novel bioactive compounds with unique three-dimensional shapes.
• Academic & Industrial R&D: A critical tool for fundamental research in organic chemistry and chemical biology at universities and corporate R&D centers.

Basic Information

Product Name	(1S,4S)-2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene
CAS No.	850409-83-5
Molecular Formula	C22H20
Molecular Weight	284.40 g/mol
Synonyms	(1S,4S)-2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene; (1S,4S)-2,5-Diphenyl-2,5-dihydro-1,4:5,8-diepoxybiphenylene; (1S,4S)-2,5-Diphenyl-2,5-dihydro-1,4:5,8-diepoxynaphthalene; (1S,4S)-Bicyclo[2.2.2]octa-2,5-diene-2,5-diphenyl; (1S,4S)-syn-2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene; 2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene, (1S,4S)-; syn-2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene
EINECS	Contact for details

Quality Control

Our (1S,4S)-2,5-Diphenylbicyclo[2.2.2]octa-2,5-diene is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity analysis (HPLC/Chiral GC), structural confirmation, and impurity profiling. A detailed Certificate of Analysis (COA) documenting identity, purity (typically >97% by HPLC), enantiomeric excess, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.