Description

2-n-Cbz-2-Methylpropane-1,2-Diamine is a high-purity, protected diamine building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and sophisticated fine chemicals. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for peptide-mimetic and chiral synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in protease inhibitor and antiviral research.
• Peptidomimetic Chemistry: Used to introduce sterically hindered, protected diamine moieties into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal complexation.
• Agrochemical Research: Employed in the development of new active ingredients with specific stereochemical requirements.
• Polymer Modification: Can be used to introduce amine functionality into specialty polymers and resins.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry laboratories.

Basic Information

Product Name	2-n-Cbz-2-Methylpropane-1,2-Diamine
CAS No.	850203-57-5
Molecular Formula	C13H20N2O2
Molecular Weight	236.31 g/mol
Synonyms	N2-(Benzyloxycarbonyl)-2-methylpropane-1,2-diamine; 2-[(Benzyloxy)carbonyl]amino]-2-methylpropane-1,3-diamine; 2-(Cbz-Amino)-2-methyl-1,3-propanediamine; 2-Methyl-2-[(phenylmethoxy)carbonyl]amino]-1,3-propanediamine; Cbz-Protected 2-Methyl-1,3-diaminopropane; 1,3-Diamino-2-methyl-2-propyl carbamate, N-benzyloxycarbonyl derivative
EINECS	Contact for details

Quality Control

Our 2-n-Cbz-2-Methylpropane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.