Description

S-2-n-Cbz-Propane-1,2-Diamine-Hcl CAS NO 850033-71-5 is a high-purity, chiral diamine derivative protected with a carboxybenzyl (Cbz) group. This compound serves as a critical chiral building block and intermediate in sophisticated organic synthesis, particularly for the construction of complex molecules with defined stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs), peptide mimetics, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, especially for neurological and antiviral targets.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics where the chiral 1,2-diamine structure is incorporated into the backbone.
• Catalyst & Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis, such as in hydrogenation or C-C bond-forming reactions.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Agrochemical Development: Potential intermediate in the synthesis of chiral active ingredients for crop protection agents.

Basic Information

Product Name	S-2-n-Cbz-Propane-1,2-Diamine Hydrochloride
CAS No.	850033-71-5
Molecular Formula	C11H17ClN2O2
Molecular Weight	244.72 g/mol
Synonyms	(S)-1-(((Benzyloxy)carbonyl)amino)-2-aminopropane hydrochloride; (S)-2-((((Benzyloxy)carbonyl)amino)propylamine hydrochloride; (S)-N-Cbz-1,2-Diaminopropane hydrochloride; (S)-Nα-Cbz-1,2-diaminopropane HCl; (S)-1-Amino-2-((((benzyloxy)carbonyl)amino)propane hydrochloride; S-2-Cbz-Amino-1,2-diaminopropane HCl; (S)-2-CbzNH-Propan-1,2-diamine HCl
EINECS	Contact for details

Quality Control

Our S-2-n-Cbz-Propane-1,2-Diamine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.