Description

2-Chloroquinoline-6-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for constructing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions, amide bond formation, and other transformations to introduce the chloroquinoline-carboxylic acid moiety.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	2-Chloroquinoline-6-Carboxylic Acid
CAS No.	849996-80-1
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	6-Carboxy-2-chloroquinoline; 2-Chloro-6-quinolinecarboxylic acid; 2-Chloroquinoline-6-carboxylic acid; Quinoline-6-carboxylic acid, 2-chloro-; 849996-80-1
EINECS	Contact for details

Quality Control

Our 2-Chloroquinoline-6-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.