Description

(+)-1,2-Bis((2S,5S)-2,5-Diphenylphospholano)Ethane(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is a high-purity, chiral bisphosphine ligand-rhodium complex, specifically designed as a highly efficient and enantioselective catalyst for asymmetric hydrogenation and other transition metal-catalyzed reactions. Its value lies in providing exceptional stereochemical control, enabling the production of single-enantiomer intermediates critical for advanced pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable and reproducible catalytic performance.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing enantiomerically pure active pharmaceutical ingredients (APIs), especially in cardiovascular and central nervous system drugs.
• Agrochemical Production: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Enables the production of high-value chiral building blocks and aroma chemicals.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Process Development and Scale-up: Suitable for optimizing and transferring catalytic processes from laboratory to pilot plant and production scale.

Basic Information

Product Name	(+)-1,2-Bis((2S,5S)-2,5-Diphenylphospholano)Ethane(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate
CAS No.	849950-53-4
Molecular Formula	C46H48BF4P2Rh
Molecular Weight	852.52 g/mol
Synonyms	(S,S)-Et-FerroPhos Rh(COD)BF4; (S,S)-1,2-Bis(2,5-diphenylphospholano)ethane(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; Rhodium(I)-(S,S)-Et-FerroPhos(COD) tetrafluoroborate; (S,S)-Et-FerroPhos Rhodium Catalyst; (S,S)-Et-FerroPhos-Rh(COD)BF4; (S,S)-Et-FerroPhos-Rh(I) complex; (S,S)-Bisphospholane Rh(COD)BF4 complex
EINECS	Contact for details

Quality Control

Our (+)-1,2-Bis((2S,5S)-2,5-Diphenylphospholano)Ethane(1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high catalytic activity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and performance data is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This material is moisture-sensitive and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	~12.1% (Theoretical)
Specific Rotation	Contact for details
Solubility	Soluble in dichloromethane, chloroform, THF; sparingly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.