Description

(+)-Dichloro[(4R)-4-(I-Propyl)-2-{(R)-2-(Diphenylphosphino)Ferrocenyl}Oxazoline](Triphenylphosphine)Ruthenium(II) is a highly specialized, chiral ruthenium complex designed for asymmetric catalysis. This compound matters because it serves as a powerful and selective catalyst for critical carbon-carbon bond-forming reactions, enabling the synthesis of enantiomerically pure intermediates. It is primarily needed by research institutions and pharmaceutical manufacturers developing advanced active pharmaceutical ingredients (APIs) and fine chemicals where stereochemical control is paramount.

Application

• Asymmetric Hydrogenation: A premier catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Key for producing chiral building blocks in the manufacture of high-value drugs, including those for cardiovascular and central nervous system disorders.
• Fine Chemical Production: Enables the synthesis of complex, optically active molecules used in agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: A vital tool for methodological development in organic synthesis and catalysis research.
• Process Chemistry Optimization: Used to develop scalable, efficient, and stereoselective manufacturing routes for chiral compounds.

Basic Information

Product Name	(+)-Dichloro[(4R)-4-(I-Propyl)-2-{(R)-2-(Diphenylphosphino)Ferrocenyl}Oxazoline](Triphenylphosphine)Ruthenium(II)
CAS No.	849921-25-1
Molecular Formula	C46H42Cl2FeNOP2Ru
Molecular Weight	882.61 g/mol
Synonyms	(R,R)-[RuCl2(PPh3)((R)-4-iPr-FerroPHOX)]; Ru-FerroPHOX Catalyst; (R,R)-RuCl2(PPh3)((R)-4-Isopropyl-FerroPHOX); Ruthenium(II) FerroPHOX complex; Chiral Ruthenium Diphosphine Oxazoline Catalyst; Asymmetric Hydrogenation Catalyst Ru(S)-4-iPr-FerroPHOX; [RuCl2((R)-4-iPr-FerroPHOX)(PPh3)]
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalysts is produced and tested under strict inert atmosphere conditions to guarantee activity and purity. We employ advanced analytical techniques including HPLC, NMR, and elemental analysis to verify chemical identity, enantiomeric purity, and catalytic performance. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This compound is easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Residual Solvents (GC)	Meets ICH guidelines
Elemental Analysis	Within theoretical ± 0.4%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.