Description

6-(Trifluoromethyl)Quinoline-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block prized for its unique trifluoromethyl-substituted quinoline scaffold. This compound is essential for introducing lipophilicity, metabolic stability, and electronic modulation into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for developing potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.
• Catalyst Ligand Development: The carboxylic acid and nitrogen moieties make it a candidate for designing novel chiral or asymmetric catalysts.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	6-(Trifluoromethyl)Quinoline-2-Carboxylic Acid
CAS No.	849818-58-2
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	2-Quinolinecarboxylic acid, 6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-quinolinecarboxylic acid; 6-Trifluoromethylquinoline-2-carboxylic acid; Quinoline-2-carboxylic acid, 6-(trifluoromethyl)-; 849818-58-2; 6-TFMQA
EINECS	Contact for details

Quality Control

Every batch of 6-(Trifluoromethyl)Quinoline-2-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and incompatible materials. Handle in accordance with good industrial hygiene and safety practice.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.