Description

1,1Bis((2R,5R)-2,5-Di-I-Propylphospholano)Ferrocene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate is a highly specialized, chiral organometallic catalyst complex. This compound is valued for its exceptional enantioselectivity and catalytic efficiency in asymmetric hydrogenation and other transition metal-catalyzed reactions. It is a critical reagent for pharmaceutical R&D and fine chemical synthesis, particularly in the production of chiral intermediates for active pharmaceutical ingredients (APIs).

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical synthesis.
• Pharmaceutical Intermediate Production: Synthesis of chiral building blocks for APIs in therapeutic areas such as oncology, cardiology, and central nervous system (CNS) disorders.
• Fine Chemical Synthesis: Enantioselective transformations in the manufacture of agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: A key tool in methodological development for new catalytic processes in organic chemistry.
• Process Chemistry Optimization: Used in scale-up studies to develop efficient and cost-effective manufacturing routes for chiral molecules.

Basic Information

Product Name	1,1Bis((2R,5R)-2,5-Di-I-Propylphospholano)Ferrocene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate
CAS No.	849773-96-2
Molecular Formula	C₃₄H₅₆BF₄FeP₂Rh
Molecular Weight	~756.33 g/mol (Contact for details)
Synonyms	(R,R)-1,1'-Bis(2,5-diisopropylphospholano)ferrocene (cyclooctadiene)rhodium(I) tetrafluoroborate; (R,R)-DIPPF-Rh(COD)BF₄; Rhodium(I)-(R,R)-1,1'-Bis(2,5-diisopropylphospholano)ferrocene cyclooctadiene tetrafluoroborate; (R,R)-Di-i-Pr-Ferrocelane Rh(COD)BF₄; Josiphos-type Rhodium Catalyst; Chiral Rhodium Ferrocenylphosphine Complex; Asymmetric Hydrogenation Catalyst Rh-001; [Rh((R,R)-DIPPF)(COD)]BF₄
EINECS	Contact for details

Quality Control

Every batch of our chiral catalyst is produced and tested under strict quality management to ensure consistent high performance and enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as Rhodium content, chiral purity, and solvent residues. Our quality systems support development under cGMP guidelines for pharmaceutical applications, ensuring traceability and reliability for critical process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (argon or nitrogen) in a cool, dry place. This material is both hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Rhodium Content	~13.6% (Theoretical)
Specific Rotation	Contact for details
Solvent Residues (GC)	Meet ICH guidelines
Moisture (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.