Description

cis-1-n-Boc-1,3-Cyclohexyldiamine is a high-purity, protected diamine building block featuring a cis-configured cyclohexane ring. This compound is critically important for its role as a chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated chiral ligands for transition metal catalysis, enabling enantioselective transformations.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
• Peptidomimetics & Macrocycle Chemistry: The protected diamine functionality is integral to creating conformationally constrained peptide analogs and cyclic compounds for drug discovery.
• Polymer Modification: Employed in the synthesis of specialty polyamides, polyurethanes, and epoxy curing agents to introduce rigidity and chirality into polymer backbones.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and linkers for studying biological systems and target engagement.

Basic Information

Product Name	cis-1-n-Boc-1,3-Cyclohexyldiamine
CAS No.	849616-22-4
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(1R,3S)-1-[(tert-Butoxycarbonyl)amino]-3-aminocyclohexane; cis-1-(Boc-amino)-3-aminocyclohexane; (1R,3S)-1-((tert-Butoxycarbonyl)amino)cyclohexane-3-amine; cis-N-Boc-1,3-diaminocyclohexane; cis-1,3-Cyclohexanediamine, 1-(BOC)-; Boc-cis-1,3-diaminocyclohexane; (1R,3S)-1-Amino-3-[(tert-butoxycarbonyl)amino]cyclohexane
EINECS	Contact for details

Quality Control

Our cis-1-n-Boc-1,3-Cyclohexyldiamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.