Description

1-Piperidinecarboxylic Acid, 4-[[[4-(2-Fluoro-4-Nitrophenoxy)-6-Methoxy-7-Quinolinyl]Oxy]Methyl]-, 1,1-Dimethylethyl Ester is a sophisticated, high-purity organic compound designed for advanced chemical synthesis. This molecule is of significant commercial interest as a key pharmaceutical intermediate, particularly in the development of targeted kinase inhibitors. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents. Our supply ensures the consistent quality and reliability required for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of kinase inhibitor drug candidates, particularly in oncology research.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Organic Synthesis: Employed in medicinal chemistry for the construction of complex quinoline and piperidine-containing molecular architectures.
• Preclinical Development: Supplied for the preparation of compounds used in pharmacokinetic, pharmacodynamic, and toxicology studies.
• Contract Manufacturing: Provided to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 4-[[[4-(2-Fluoro-4-Nitrophenoxy)-6-Methoxy-7-Quinolinyl]Oxy]Methyl]-, 1,1-Dimethylethyl Ester
CAS No.	849217-45-4
Molecular Formula	C28H30FN3O7
Molecular Weight	539.56 g/mol
Synonyms	4-[[[4-(2-Fluoro-4-Nitrophenoxy)-6-Methoxy-7-Quinolinyl]oxy]methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-({[4-(2-fluoro-4-nitrophenoxy)-6-methoxyquinolin-7-yl]oxy}methyl)piperidine-1-carboxylate; 849217-45-4; BOC-protected quinoline-piperidine intermediate; Kinase inhibitor intermediate PI3K/mTOR
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. We adhere to strict in-house specifications developed for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.