Description

Trifluoro-Methanesulfonic Acid 4-tert-Butoxycarbonylamino-Cyclohex-1-Enyl Ester is a specialized, high-value trifluoromethanesulfonate (triflate) ester derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a protected amino-cyclohexenyl precursor, enabling the controlled introduction of functionalized cyclohexene scaffolds into complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for constructing novel active ingredients and intermediates requiring stereochemical control.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the functionalized cyclohexene ring contributes to specific biological activity.
• Peptide Mimetics & Conformationally Restricted Analogs: The Boc-protected amino group and cyclohexene core are valuable for creating peptidomimetics and rigid analogs to improve metabolic stability and binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands or organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Potential monomer or building block for specialty polymers with unique thermal or chemical resistance properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis, including cross-coupling reactions and C-N bond formation studies.

Basic Information

Product Name	Trifluoro-Methanesulfonic Acid 4-tert-Butoxycarbonylamino-Cyclohex-1-Enyl Ester
CAS No.	849069-49-4
Molecular Formula	C13H20F3NO5S
Molecular Weight	359.36 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]cyclohex-1-en-1-yl trifluoromethanesulfonate; 1-Cyclohexene-1-ol, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, trifluoromethanesulfonate (ester); 4-(Boc-amino)cyclohex-1-enyl triflate; Boc-4-Aminocyclohexenyl Triflate; 4-(N-Boc-amino)cyclohex-1-enyl trifluoromethanesulfonate; Trifluoromethanesulfonic acid 4-(tert-butoxycarbonylamino)cyclohex-1-enyl ester; (4-((tert-Butoxycarbonyl)amino)cyclohex-1-en-1-yl) trifluoromethanesulfonate
EINECS	Contact for details

Quality Control

Our production of Trifluoro-Methanesulfonic Acid 4-tert-Butoxycarbonylamino-Cyclohex-1-Enyl Ester adheres to stringent quality protocols suitable for research and cGMP starting material applications. Each batch is characterized and tested to ensure high chemical purity and structural integrity. Comprehensive analytical techniques including HPLC, NMR (¹H and ¹³C), and mass spectrometry are employed. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is between 2°C and 8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.