Description

1-(Bromomethyl)-4-Chloro-2-(Methylsulfonyl)Benzene is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring reactive bromomethyl and chlorophenyl groups adjacent to an electron-withdrawing methylsulfonyl moiety, makes it a versatile precursor for constructing complex molecular frameworks. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in medicinal chemistry programs targeting sulfone-containing bioactive compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the benzyl bromide and aryl chloride functionalities allow for selective derivatization.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands for transition metal catalysis or organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized monomers or cross-linkers for advanced polymers with specific electronic or thermal properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to its reactive handles, which can be used for bioconjugation or labeling studies.

Basic Information

Product Name	1-(Bromomethyl)-4-Chloro-2-(Methylsulfonyl)Benzene
CAS No.	849035-64-9
Molecular Formula	C8H8BrClO2S
Molecular Weight	283.57 g/mol
Synonyms	4-Chloro-2-(methylsulfonyl)-1-(bromomethyl)benzene; 1-Bromomethyl-4-chloro-2-methylsulfonylbenzene; 2-(Bromomethyl)-5-chlorophenyl methyl sulfone; 4-Chloro-α-(bromomethyl)-o-(methylsulfonyl)toluene; 5-Chloro-2-[(bromomethyl)sulfonyl]toluene; Benzene, 1-(bromomethyl)-4-chloro-2-(methylsulfonyl)-; (4-Chloro-2-methylsulfonylphenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our production of 1-(Bromomethyl)-4-Chloro-2-(Methylsulfonyl)Benzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.