Description

2-Quinolin-2-Yl-1-[3-(Trifluoromethyl)Phenyl]Ethanone CAS NO 849021-38-1 is a high-value, specialized organic compound featuring a quinoline core linked to a trifluoromethylphenyl ketone moiety. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand & Catalyst Synthesis: Acts as a starting material for creating complex ligands used in catalytic systems and coordination chemistry.
• Material Science Precursor: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated quinoline structure.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Scale-Up: A fundamental building block for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	2-Quinolin-2-Yl-1-[3-(Trifluoromethyl)Phenyl]Ethanone
CAS No.	849021-38-1
Molecular Formula	C18H12F3NO
Molecular Weight	315.29 g/mol
Synonyms	1-(3-(Trifluoromethyl)phenyl)-2-(quinolin-2-yl)ethan-1-one; 2-Quinolin-2-yl-1-[3-(trifluoromethyl)phenyl]ethanone; 2-(2-Oxo-2-(3-(trifluoromethyl)phenyl)ethyl)quinoline; Ethanone, 1-[3-(trifluoromethyl)phenyl]-2-(2-quinolinyl)-; 849021-38-1; α-(2-Quinolyl)-3'-(trifluoromethyl)acetophenone
EINECS	Contact for details

Quality Control

Our production of 2-Quinolin-2-Yl-1-[3-(Trifluoromethyl)Phenyl]Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and reliable supply chain integrity makes us a trusted partner for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.