Description

4-(4-Boc-Aminophenyl)Phenol is a high-purity, protected aniline derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for creating active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and targeted therapy research.
• Peptide Mimetics & PROTACs: Serves as a versatile linker or spacer component in the design of proteolysis-targeting chimeras (PROTACs) and peptide-like molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of high-performance polymers and liquid crystal materials.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring a protected aromatic amine functionality.

Basic Information

Product Name	4-(4-Boc-Aminophenyl)Phenol
CAS No.	848853-75-8
Molecular Formula	C17H19NO3
Molecular Weight	285.34 g/mol
Synonyms	4-(4-((tert-Butoxycarbonyl)amino)phenyl)phenol; 4'-Hydroxy-[1,1'-biphenyl]-4-amine, N-BOC-protected; tert-Butyl (4'-hydroxy-[1,1'-biphenyl]-4-yl)carbamate; 4-(4-(Boc-amino)phenyl)phenol; BOC-4-Aminobiphenyl-4'-ol; N-Boc-4,4'-diaminobiphenyl-4'-ol; [1,1'-Biphenyl]-4-amine, 4'-hydroxy-, N-[(1,1-dimethylethoxy)carbonyl]-; BOC-DAHB
EINECS	Contact for details

Quality Control

Our 4-(4-Boc-Aminophenyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.