Description

4-Chloro-6-Hydroxyquinazoline is a high-purity quinazoline derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tyrosine kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its bioactive quinazoline core.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening.
• Material Science Research: Investigated as a monomer or precursor for organic electronic materials and photoactive compounds.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme inhibition and cellular signaling pathways.

Basic Information

Item	Details
Product Name	4-Chloro-6-Hydroxyquinazoline
CAS No.	848438-50-6
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	6-Hydroxy-4-chloroquinazoline; 4-Chloro-6-quinazolinol; 4-Chloroquinazolin-6-ol; Quinazoline, 4-chloro-6-hydroxy-; 848438-50-6; 4-Chloro-6-hydroxy-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Hydroxyquinazoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.