Description

n-(4-Chloro-3-Cyano-7-Ethoxy-6-Quinolinyl) Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-based molecular structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific enzyme pathways.
• Organic Synthesis Building Block: Utilized in research and development for constructing novel heterocyclic compounds due to its reactive chloro, cyano, and acetamide functional groups.
• Agrochemical Research: Serves as a starting material or intermediate in the development of new-generation herbicides or pesticides with quinoline cores.
• Material Science Applications: Investigated for use in the synthesis of organic semiconductors or light-emitting materials given its conjugated quinoline system.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or non-GMP conditions.

Basic Information

Product Name	n-(4-Chloro-3-Cyano-7-Ethoxy-6-Quinolinyl) Acetamide
CAS No.	848133-76-6
Molecular Formula	C₁₄H₁₀ClN₃O₂
Molecular Weight	287.70 g/mol
Synonyms	4-Chloro-3-cyano-7-ethoxy-6-quinolinylacetamide; 2-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide; Acetamide, N-(4-chloro-3-cyano-7-ethoxy-6-quinolyl)-; 848133-76-6; 6-Acetamido-4-chloro-7-ethoxyquinoline-3-carbonitrile; N-(4-Chloro-3-cyano-7-ethoxyquinolin-6-yl)acetamide
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-3-Cyano-7-Ethoxy-6-Quinolinyl) Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation or moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.