Description

tert-Butyl 5-Hydroxynaphthalen-1-Ylcarbamate is a specialized organic building block featuring a naphthalene core functionalized with both a hydroxyl group and a tert-butyl carbamate protecting group. This compound matters as a versatile and crucial intermediate in advanced organic synthesis, particularly for constructing complex molecules where selective protection and deprotection strategies are required. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), drug candidates, and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those with naphthalene-based structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides where its aromatic system contributes to biological activity.
• Organic Synthesis Reagent: Serves as a protected amine precursor in complex organic reactions, including peptide coupling and heterocycle formation.
• Material Science Research: Potential monomer or intermediate for the development of specialty polymers, dyes, and advanced organic materials.
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and affinity tags for studying biological systems.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	tert-Butyl 5-Hydroxynaphthalen-1-Ylcarbamate
CAS No.	848086-82-8
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	1-Naphthol, 5-[[(1,1-Dimethylethoxy)carbonyl]amino]-; 5-((tert-Butoxycarbonyl)amino)-1-naphthol; 5-(Boc-amino)-1-naphthol; 5-Amino-1-naphthol tert-butyl carbamate; Boc-5-Amino-1-naphthol; tert-Butyl (5-hydroxy-1-naphthyl)carbamate; N-Boc-5-amino-1-naphthol; 1-Naphthalenol, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Hydroxynaphthalen-1-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications, and our quality commitment ensures reliable supply for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.