Description

Methanesulfonamide, 1,1,1-Trifluoro-n-[1,2,3,4-Tetrahydro-1-(2-Methylpropyl)-7-Quinolinyl]- is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethanesulfonamide and tetrahydroquinoline structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system and metabolic disorders. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those requiring a fluorinated sulfonamide moiety.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead compound optimization for enhanced potency and metabolic stability.
• Process Chemistry & Scale-Up: Serves as a critical raw material for process development and the manufacture of active pharmaceutical ingredients (APIs) under GMP conditions.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biochemical assays.
• Agrochemical Research: Exploration of applications in the synthesis of novel agrochemicals with improved efficacy.
• Academic & Institutional R&D: Utilized in universities and research institutes for cutting-edge organic synthesis and drug discovery projects.

Basic Information

Product Name	Methanesulfonamide, 1,1,1-Trifluoro-n-[1,2,3,4-Tetrahydro-1-(2-Methylpropyl)-7-Quinolinyl]-
CAS No.	848080-35-3
Molecular Formula	C₁₄H₁₇F₃N₂O₂S
Molecular Weight	334.36 g/mol
Synonyms	1,1,1-Trifluoro-N-[1,2,3,4-tetrahydro-1-(2-methylpropyl)-7-quinolinyl]methanesulfonamide; 1,1,1-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-7-quinolinyl)methanesulfonamide; 1-(Isobutyl)-1,2,3,4-tetrahydro-7-quinolinyl trifluoromethanesulfonamide; Trifluoromethanesulfonamide, N-[1,2,3,4-tetrahydro-1-(2-methylpropyl)-7-quinolinyl]-; 848080-35-3; UNII-9I1VH5N71F
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, 1,1,1-Trifluoro-n-[1,2,3,4-Tetrahydro-1-(2-Methylpropyl)-7-Quinolinyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full traceability are provided. We support development and commercial projects with material produced to meet research-grade, GMP-starting material, or custom purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.