Description

7-Bromo-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated quinolinone structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Serves as a key scaffold for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of specialty chemicals and advanced materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Synthesis: Acts as a versatile reagent for introducing the bromo-trifluoromethyl-quinolinone moiety into more complex molecular architectures via cross-coupling and other reactions.

Basic Information

Product Name	7-Bromo-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
CAS No.	847900-73-6
Molecular Formula	C10H5BrF3NO
Molecular Weight	292.06 g/mol
Synonyms	7-Bromo-4-(trifluoromethyl)-2-quinolinone; 7-Bromo-4-(trifluoromethyl)-1H-quinolin-2-one; 7-Bromo-4-(trifluoromethyl)-2(1H)-quinolinone; 2(1H)-Quinolinone, 7-bromo-4-(trifluoromethyl)-; 847900-73-6; 7-Bromo-4-trifluoromethyl-1,2-dihydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.