Description

Chloro(Triphenylphosphine) [2-(2′-Amino-1,1′-Biphenyl)]Palladium(II) is a highly active and versatile Buchwald-Hartwig amination catalyst, essential for constructing carbon-nitrogen bonds in complex organic molecules. Its value lies in enabling efficient, high-yield cross-coupling reactions under mild conditions, which is critical for streamlining pharmaceutical and advanced material synthesis. This catalyst is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for Buchwald-Hartwig amination in the production of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides requiring aryl amine motifs.
• Material Science Research: Facilitates the creation of novel organic semiconductors, conductive polymers, and OLED materials.
• Ligand and Complex Preparation: Serves as a precursor for generating other specialized palladium catalysts and phosphine ligands.
• Academic & Industrial R&D: A staple reagent for method development and exploring new C-N bond-forming reactions in laboratory settings.
• Scale-up Process Chemistry: Employed in pilot plants and manufacturing for the scalable, reliable production of aryl amine compounds.

Basic Information

Product Name	Chloro(Triphenylphosphine) [2-(2′-Amino-1,1′-Biphenyl)]Palladium(II)
CAS No.	847616-84-6
Molecular Formula	C30H26ClNPPd
Molecular Weight	573.36 g/mol
Synonyms	Buchwald Palladacycle; Chloro[2-(2-aminobiphenyl)](triphenylphosphine)palladium(II); Pd-PEPPSI-IPr (related precatalyst class); Palladium(II) Chloride (Triphenylphosphine)(2-Aminobiphenyl) Complex; G3-XantPhos Pd Precursor (related); Aminobiphenyl Palladacycle Chloride; [2-(2-Aminophenyl)phenyl]chloro(triphenylphosphine)palladium; CataCXium Pd Precursor
EINECS	Contact for details

Quality Control

Our Chloro(Triphenylphosphine) [2-(2′-Amino-1,1′-Biphenyl)]Palladium(II) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot is analyzed to confirm identity, purity, and performance in standard amination reactions. Certificates of Analysis (COA) detailing assay, impurity profile, and residual solvent content are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and decomposition. The container should be kept in a cool, dry, and well-ventilated place separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange-brown crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd content)	Min. 18.0%
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.