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S-3-Cbz-Aminopiperidine Hcl CAS NO 847454-42-6
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CAS No.:847454-42-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
S-3-Cbz-Aminopiperidine Hcl is a high-purity chiral piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine functionality on a stereochemically defined scaffold, enabling the efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning the properties of lead compounds.
Application
- Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder therapeutics.
- Peptidomimetic Chemistry: Used to introduce constrained, nitrogen-containing ring systems into peptide backbones to enhance metabolic stability and bioavailability.
- Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
- Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
- Chemical Biology Probes: Useful for creating tool compounds and probes to study enzyme function and biological pathways.
- Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high enantiomeric purity and reliable quality.
Basic Information
| Product Name | S-3-Cbz-Aminopiperidine Hcl |
| CAS No. | 847454-42-6 |
| Molecular Formula | C13H19ClN2O2 |
| Molecular Weight | 270.75 g/mol |
| Synonyms | (S)-1-[(Benzyloxy)carbonyl]-3-aminopiperidine hydrochloride; (S)-3-[(Benzyloxycarbonyl)amino]piperidine hydrochloride; (S)-N-Cbz-3-Aminopiperidine hydrochloride; (S)-3-(Cbz-Amino)piperidine HCl; (3S)-1-[(Phenylmethoxy)carbonyl]-3-piperidinamine hydrochloride; (S)-1-Cbz-3-Aminopiperidine HCl; (S)-3-Amino-1-Cbz-piperidine hydrochloride; S-3-Cbz-Amino-piperidine HCl |
| EINECS | Contact for details |
Quality Control
Our S-3-Cbz-Aminopiperidine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical development and other advanced research applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Conforms |
| Identification (IR) | Conforms |
| Assay (HPLC) | ≥98.0% |
| Chiral Purity (HPLC) | ≥99.0% ee |
| Water Content (KF) | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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