Description

8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine hydrochloride is a high-purity organic compound serving as a critical building block in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel therapeutic agents, particularly within the central nervous system (CNS) and neuropharmacology domains. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the development of potential APIs, particularly for CNS-targeted therapies.
• Contract Synthesis: Supplied to CROs and CDMOs for custom synthesis projects and process development.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic Research: Employed in university and institutional labs for pharmacological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine hydrochloride
CAS No.	847173-36-8
Molecular Formula	C10H13ClFN
Molecular Weight	201.67 g/mol
Synonyms	8-Fluoro-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride; 1H-3-Benzazepine, 8-fluoro-2,3,4,5-tetrahydro-, hydrochloride; 8-Fluoro-1,2,4,5-tetrahydro-3H-3-benzazepine hydrochloride; 8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine HCl; Benzoazepine derivative 847173-36-8
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[b]azepine hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.