Description

5-[[(7-Chloro-4-Quinolinyl)Sulfanyl]Methyl]-4-Methyl-4H-1,2,4-Triazole-3-Thiol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining quinoline and triazole moieties. This compound is critical for research and development in medicinal chemistry, offering a versatile scaffold for the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly for applications in antimicrobial and antiparasitic drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel quinoline-triazole hybrid compounds for potential drug candidates.
• Antimicrobial Research: Used in R&D programs targeting the development of new antibacterial and antifungal agents, leveraging the bioactive quinoline core.
• Antiparasitic Agent Development: Investigated as a precursor for compounds with potential activity against malaria and other parasitic diseases.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and biological pathway modulation.
• Organic Synthesis: Acts as a versatile synthon for constructing complex heterocyclic systems in medicinal and process chemistry.

Basic Information

Product Name	5-[[(7-Chloro-4-Quinolinyl)Sulfanyl]Methyl]-4-Methyl-4H-1,2,4-Triazole-3-Thiol
CAS No.	845885-91-8
Molecular Formula	C13H11ClN4S2
Molecular Weight	322.83 g/mol
Synonyms	5-[(7-Chloro-4-quinolylthio)methyl]-4-methyl-4H-1,2,4-triazole-3-thiol; 4-Methyl-5-[[(7-chloro-4-quinolinyl)thio]methyl]-4H-1,2,4-triazole-3-thiol; 5-((7-Chloroquinolin-4-ylthio)methyl)-4-methyl-4H-1,2,4-triazole-3-thiol; 845885-91-8; Quinoline-triazole thioether derivative
EINECS	Contact for details

Quality Control

Our 5-[[(7-Chloro-4-Quinolinyl)Sulfanyl]Methyl]-4-Methyl-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.